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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL23
All Species:
13.64
Human Site:
T106
Identified Species:
25
UniProt:
Q16540
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16540
NP_066957.3
153
17781
T106
L
A
H
G
Q
T
F
T
F
P
D
L
F
P
E
Chimpanzee
Pan troglodytes
XP_508219
185
20823
T138
L
A
H
G
Q
T
F
T
F
P
D
L
F
P
E
Rhesus Macaque
Macaca mulatta
XP_001092196
153
17778
T106
L
A
H
G
Q
T
F
T
F
P
D
L
F
P
E
Dog
Lupus familis
XP_540784
195
22748
T148
L
A
H
G
Q
T
F
T
F
P
D
L
F
P
E
Cat
Felis silvestris
Mouse
Mus musculus
O35972
146
17103
A100
K
V
A
Y
V
Q
L
A
H
G
Q
T
F
T
F
Rat
Rattus norvegicus
Q63750
146
17032
A100
K
V
A
Y
V
Q
L
A
H
G
Q
T
F
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517094
106
11828
F60
A
H
G
Q
T
F
T
F
P
D
L
F
P
K
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089781
153
18185
Q106
L
G
Q
G
Q
T
F
Q
F
P
E
L
F
P
Q
Zebra Danio
Brachydanio rerio
Q6IQS9
153
18239
Q106
L
A
Q
Q
Q
T
F
Q
F
P
D
I
F
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W021
150
17859
F104
T
L
P
R
E
E
S
F
V
F
P
D
F
F
S
Honey Bee
Apis mellifera
XP_001120599
144
17348
K98
I
A
Y
V
V
L
P
K
D
Q
S
F
K
F
P
Nematode Worm
Caenorhab. elegans
Q9GYS9
159
19076
K109
I
A
Y
V
F
M
S
K
G
F
E
F
S
Y
P
Sea Urchin
Strong. purpuratus
XP_792235
148
17360
Q102
Y
V
T
L
A
E
G
Q
T
F
E
F
P
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
92.1
64
N.A.
83.6
84.9
N.A.
30.7
N.A.
65.3
61.4
N.A.
40.5
40.5
32.7
49
Protein Similarity:
100
82.1
96
72.3
N.A.
88.2
89.5
N.A.
47
N.A.
82.3
78.4
N.A.
56.2
60.7
53.4
65.3
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
0
N.A.
66.6
73.3
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
6.6
N.A.
80
80
N.A.
13.3
20
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
54
16
0
8
0
0
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
39
8
0
8
0
% D
% Glu:
0
0
0
0
8
16
0
0
0
0
24
0
0
0
39
% E
% Phe:
0
0
0
0
8
8
47
16
47
24
0
31
70
16
16
% F
% Gly:
0
8
8
39
0
0
8
0
8
16
0
0
0
0
0
% G
% His:
0
8
31
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
16
0
0
0
0
0
0
16
0
0
0
0
8
8
8
% K
% Leu:
47
8
0
8
0
8
16
0
0
0
8
39
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
0
8
47
8
0
16
47
16
% P
% Gln:
0
0
16
16
47
16
0
24
0
8
16
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
16
0
0
0
8
0
8
0
8
% S
% Thr:
8
0
8
0
8
47
8
31
8
0
0
16
0
16
0
% T
% Val:
0
24
0
16
24
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
16
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _